Evidence & Clinical Trials
A curated list of clinical trials, meta‑analyses, and practice‑based studies supporting Collaborative Care (CoCM). Each item links to a DOI or a PubMed search.
Foundational Evidence & Reviews
- Collaborative care for depression and anxiety problems (Cochrane Review)
- Collaborative care for depression: a cumulative meta-analysis and review of longer-term outcomes
- PHQ primary care study: validation and utility of a self-report version of PRIME-MD
- Collaborative care to improve the management of depressive disorders
- Transforming mental health care at the interface with general medicine: the Collaborative Care model
Implementation & Practice-Based Evidence
- Collaborative care management of late-life depression in the primary care setting (IMPACT)
- Time to remission for depression with collaborative care management in primary care
- Impact of collaborative care for depression on clinical, functional, and work outcomes: a practice-based evaluation
- Implementation of a care management model for depression at two primary care clinics
- PHQ-9 response curve: rate of improvement for depression treatment with collaborative care management
- Collaborative care for adolescents with depression in primary care
- Collaborative care for patients with depression and chronic illnesses (TEAMcare)
- Telemedicine-based collaborative care for depression in rural federally qualified health centers
- Telemedicine-based collaborative care for posttraumatic stress disorder
- Collaborative care management of major depression among low-income, predominantly Hispanic subjects with diabetes
Workforce & Outreach
Payment & Cost-Effectiveness
- Quality improvement with pay-for-performance incentives in integrated behavioral health care
- Cost-effectiveness of a multicondition collaborative care intervention for managing depression and chronic disease
- Cost-effectiveness of collaborative care for the treatment of major depressive disorder in primary care
Co-occurring Conditions
- Referral for substance abuse treatment and depression improvement among patients with co-occurring disorders
- Collaborative care for opioid and alcohol use disorders in primary care (SUMMIT)
- Integrated collaborative care for comorbid major depression and cancer (SMaRT Oncology-2)
- Effectiveness of collaborative care for depression in HIV clinics
- Stepped collaborative care for acutely injured trauma survivors
Additional Practice-based Studies
- Correlation between mental health comorbidity screening scores and clinical response in collaborative care
- Age of depressed patient does not affect clinical outcome in collaborative care management
- Increased anxiety and length of treatment associated with depressed patients readmitted to collaborative care
- Prolonged care management for depression: enrolled for more than one year
- Patient self-assessment factors predictive of persistent depressive symptoms 6 months after enrollment
UW AIMS — Evidence & Resources
If you are interested in learning more about CoCM research and clinical data, please reach out to us at hello@$profoundinstitute.org.
